Abstract: Based on the literature, this paper reveals the hotspots and trend analysis of Phellodendron research. The literatures of academic journals from 1959 to 2021 were searched on CNKI with “Huang Bai (Phellodendron)” as the key word, and the literatures were analyzed with the visual statistics of CNKI and CiteSpace software. The results showed that: (1) There were three stages in the research literature of Phellodendron in the past 60 years: germination stage, rapid growth stage and decline stage. From 1959 to 1997, the research literature of Phellodendron was in the germination stage, with an average number of articles below 10, and even the number was zero in many years. From 1998 to 2007, it was the rapid growth stage, and the number of articles published increased rapidly, reaching the peak of 57 articles in 2007. From 2008 to 2021, the number of published articles decreased year by year, with the lowest value reaching 22, but the number was still higher than that of the first stage. (2) The research level of Phellodendron was higher than other fields, with emphasis on traditional Chinese pharmacology and traditional Chinese medicine. (3) Currently, the current research focus of Phellodendron was its medicinal value and medicinal components, and the future research trend would focus on the development and utilization of quality on the basis of medicinal value. The single development and utilization model of Phellodendron can easily lead to a short development, which would restrict the research progress of Phellodendron.