Abstract: Monochamus alternatus is one of the main vector insects transmitted by Bursaphelenchus xylophilus. In order to control the transmission of pine wood nematode disease more effectively, the virulence of 6 strains of Beauveria bassiana from different sources to Monochamus alternatus was compared, and the strains with the best pathogenicity were selected and mixed with 3 kinds of polymer materials to prepare microcapsules. The adhesion of different microcapsules on the body surface of scleroderma sichuanensis and the indoor infection effect on Monochamus alternatus were compared, and the Beauveria bassiana microcapsules with the best infection effect were applied to the forest control experiment. The results showed that strain B2 isolated from the susceptible body of Monochamus alternatus was superior to other strains in growth characters and pathogenicity to Monochamus alternatus. The surface adhesion rate of sodium alginate microcapsule to scleroderma sichuanensis was 63%, and the infection rate of Monochamus alternatus was 60% in laboratory test. This study proved the feasibility of using natural enemy insects to carry pathogenic fungi microcapsules to control stem borers.rol stem borers.