Abstract: In order to establish a container seedling raising technical system suitable for Sapium sebiferum in southern Sichuan, this study analyzed the effects of substrate formulation, slow-release fertilizer amount, container specification and density on the growth of container seedlings of Sapium sebiferum by factorial experiment design, and the container seedling density was studied. The results showed that the growth of container seedlings of one-year-old Sapium sebiferum was significantly affected by three factors: substrate formulation, container specification and slow-release fertilizer amount, and their interactions. Based on the single factor mean value analysis, the mean values of seedling height and ground diameter of substrate formulation A1 （coconut bran 1: peat 1: soil 1） were significantly higher than those of other substrate formulations. The seedling height and height-diameter ratio increased with the increase of slow-release fertilizer level. The seedling height, ground diameter and height-diameter ratio of 10.0 × 13.5 cm container specification were significantly better than other specifications. A1 substrate could be used to obtain high-quality seedlings with low application of slow-release fertilizer amount （1 kg/m³） and medium-sized container （10.0 × 13.5 cm）, which could save the seedling cost. When the container seedling placement density of Sapium sebiferum was （6 × 6） /m², the seedling height, ground diameter and height-diameter ratio were the best. With the increase of container seedling placement density, the ground diameter and height-diameter ratio both decreased significantly. The most suitable combination of factors for container seedling raising of Sapium sebiferum in southern Sichuan was as follows: the substrate formulation was coconut bran 1: peat 1: soil 1, the slow-release fertilizer amount was 3 kg/m³, and the specification of non-woven fabric container was （10.0 × 13.5） cm, and the container placement density was 6 × 6 /m².