Abstract: According to the regional differences, 8 Sichuan pepper orchards were selected to investigate the spatial dynamic trend of the occurrence and prevalence of prickly ash rust, and the field control experiments were carried out. The results showed that there were two trends in the spatial dynamic trend of prickly ash rust in Sichuan Province: In the low-altitude areas, the disease index kept rising until the end of September, and then decreased slightly in October, The disease index had a maximum of 81.26 in mid-November, and then decreased gradually; In the high-altitude areas, the disease index increased continuously to a peak of 85.68 before mid-to-late September, and then decreased slowly; In different Sichuan pepper varieties, the disease indices of ‘Zhenglujiao’ and ‘Dahongpao’ were more serious than that of ‘Jiuyeqing’; In terms of field control effect, the mixed treatment of 75% trifloxystrobin ·tebuconazole with 3000 dilution and 30% pyraclostrobin ·tebuconazole with 1500 dilution showed the best control effect on Prickly ash rust, the average control effect was 80.71%, and the control effect on ‘Jiuyeqing’ was higher than that on ‘Zhenglujiao’. This study showed that prickly ash rust was more prevalent in the low-altitude area of Sichuan, ‘Jiuyeqing’ was more resistant to prickly ash rust than ‘Zhenglujiao’ and ‘Dahongpao’, the mixtures of 75% trifloxystrobin · tebuconazole and 30% pyraclostrobin · tebuconazole were screened as the control agents of prickly ash rust for the first time in Sichuan Province.