Abstract: Since 1960s, many types of nature reserves have been successively established in Sichuan Province, including nature reserves, forest parks, wetland parks, geological parks and scenic resorts and historic sites. Due to the lack of unified planning and coordination in the construction of protected areas, the overlapping among various protected areas is prominent, and the contradiction between protection and development is increasingly prominent. In order to effectively solve the spatial overlapping and overlapping of Sichuan nature reserves and the contradiction left over from history, the spatial distribution pattern of five major nature reserves in Sichuan Province was analyzed by using geographic information technology. The results showed that the spatial distribution of nature reserves was relatively concentrated and contiguous in the high mountains and plateaus of western Sichuan and scattered in Chengdu plain and hilly areas in the middle of the basin, and the area was small, which was characterized by more in the west and less in the east. The distribution of nature reserves in Sichuan was obviously related to the degree of regional economic development and population distribution.