Abstract: Studies were made of the content difference of soluble polysaccharides, total flavonoids and total saponins in leaves pricked from Cyclocarya paliurus trees at different ages in different months in Northern Guangxi, aiming to find the suitable tree age and picking time. The combinations with highest yield of each component were selected from three different harvesting time and three different harvesting ages by comparative test and variance analysis. The results showed that the soluble polysaccharides were higher when the tree age was 4 years, the total flavonoids and saponins were higher when the tree age was 2 years and the harvesting time was about November each year. The selected local asexual families could produce higher soluble sugar, flavonoids and saponins in a specific period. At different picking time and tree age, the utilization rate of C. paliurus leaves could be improved. The asexual families selected in this experiment could be used as excellent families for breeding, which would lay a foundation for the extraction of Chinese medicinal ingredients from C. paliurus leaves and the selection of excellent families in the future.