Abstract: The influencing factors of grassland desertification in Northwest Sichuan were analyzed by the graphic overlay method of superposition climate map, vegetation map and desertification land distribution map,and the specific range of desert area was determined in Northwest Sichuan Plateaus. On this basis, the sandy areas in Northwest Sichuan Plateau were divided into 3 management zones with geology and geomorphology as the dominant factors in combination with the distribution of desertification land. The first management zone was Seda-Shiqu hilly plateau desertification area. The second was Ruoergai and Hongyuan flat plateau desertification zone. The last was Litang and Batang mountain primary desertification zone.The strategy of desertification prevention and control measures was proposed according to the characteristics of desertification. This prevention and control measures were in the hope of providing scientific reference for the smooth implementation of desertification control projects in Northwest Sichuan.